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90% Performance Improvement! Electronic Lab Notebook (ELN) Gets Historic Speed-Up

by IndustryNews Center

Electronic Lab Notebook (ELN) is an essential tool in modern laboratories for recording experimental data, managing experimental plans and tracking experimental results. However, in traditional ELN platforms, page responsiveness often becomes a bottleneck that restricts work efficiency. To solve this problem, we have launched iLabPower ELN 4.0.

Electronic laboratory notebook ELN 4.0 based on cloud-native solutions for a new design planning, in the system architecture has been comprehensively upgraded, faster, more stable. ELN 4.0 uses a comprehensive containerized deployment approach, so that the application has the ability to rapidly expand horizontally and automatically scaling capacity, the business process using the industry standard Kubernetes for task scheduling, substantially improving the ELN availability, flexibility, security; especially in terms of performance, it has successfully broken through the page response speed bottleneck, realizing a historic speed-up, with a performance increase of 95%!

We have collected the average response time data of the relevant pages of ELN platform after the revamped electronic lab notebook. From the chart data, we can clearly see that the response time of ELN-related pages after the revision has been significantly shortened, and the average page response time is only 0.2 seconds!

Taking the test task page as an example, the average response time of this page was reduced to only 0.136 seconds, and similarly, the pages of Sample Center, Experiment Center List, and My Test Delivery have also achieved similar significant speed-up effects.

In ELN 4.0, the average response time for the Management Center – Member Management page has been significantly reduced to only 0.329 seconds. In addition, the average response time for the Approval of Experiments page is only 0.346 seconds after the revision, which significantly improves the efficiency of the approval process.

The release of ELN 4.0 breaks through the bottleneck of the traditional ELN platform in terms of page response time, dramatically improves the efficiency of data recording and experimental management, significantly optimizes the work experience of laboratory workers, and provides more efficient support for scientific research.

It is our goal to provide lab workers with better tools to help promote the development of scientific research. Although the revamped ELN has achieved significant speedups, we will continue to improve and optimize the performance of ELN to meet the ever-changing and growing needs of laboratories as science and technology rapidly evolve.

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NeoTrident passed ISO27001 certification, information security management capability is internationally recognized!

by CompanyNews Center

Recently, Beijing NeoTrident and its holding company Suzhou NeoTrident Software Co., Ltd. have officially passed the ISO/IEC 27001:2013 (Information Security Management System) certification audited by BSI (British Standards Institution)! This international certification not only indicates that Trunet’s information security protection ability has been recognized by international authoritative organizations, but also means that Trunet, as an information technology enterprise, is more secure and reliable while taking into account high quality and efficiency.

In recent years, the rapid development and popularization of information technology has brought unprecedented changes to human life, production methods and business models, while some brand-new risks of network threats, data leakage and frauds also come along. Therefore, in order to obtain guaranteed information technology services, security capability is the top priority.

NeoTrident has been focusing on the development and innovation of information technology in the field of life sciences and material sciences for nearly two decades, and has provided more than 1,000 R&D institutes/enterprises in China with a full range of comprehensive information technology solutions and services, including computational simulation and data modeling, scientific research and innovation and quality compliance, which have helped users to improve their management, decision-making, and innovation in the fields of research and development, process, testing, production, etc. NeoTrident has been trusted by the industry for a long time and has been able to provide a wide range of information technology solutions and services. As a long-time trusted informationization and digitalization service partner of industrial customers, Trunsun is constantly improving and upgrading its own information security management level while putting forward higher requirements on the company’s products, technologies and service levels. The ISO/IEC 27001:2013 (Information Security Management System) certification is also an audit and certification for the whole process and business line within Trunsun.

ISO27001 certification is regarded as a rigorous, authoritative and widely accepted and applied system certification standard in the field of information security in the international arena. It carries out multi-dimensional assessment from the aspects of organization management, cryptographic control, human resources security, asset management, access control, physical and environmental security, and operational security, etc., which requires the enterprises to construct a high-specification information security system, and to ensure the user’s Information security and high stability of operation system. The senior leadership of Trunsun attaches great importance to the construction of the information security management system, and all departments of the company work closely with each other to formulate a set of effective information security management system in strict accordance with the requirements of the system and in combination with the actual situation of the company. At present, a green security network has been fully spread in the company, covering the whole business process of the company’s various product lines, involving system development, testing, implementation, operation and maintenance, as well as security technology protection and so on.

It is worth mentioning that the passing of this certification also means that iLabPower Collaborative Innovation Cloud Community, a cloud computing-based scientific research collaboration and innovation platform under Chuangteng Technology, has stepped into the ranks of the domestic laboratory informationization management and security in the field of life science and materials science. iLabPower Collaborative Innovation Cloud Community covers: EDM Experimental Data Management System, PM Project Management System, CMS Compound Management System, CIM Project Management System, CMS Compound Management System, CIM Project Management System and CIM Project Management System, The iLabPower Collaborative Innovation Cloud Community is a digital collaboration platform covering: EDM Experimental Data Management System, PM Project Management System, CMS Compound Management System, CIMS Laboratory Material Management System, PMS Procurement Management System, and ILM Instrument Lifecycle Management System. All modules realize unified planning and reserved interfaces, solving the problem of data silos between systems. At present, this platform has been adopted by many domestic pharmaceutical companies, universities and research institutes.

Trunsun has always believed that only by continuously improving its comprehensive management level can it respond to today’s complex and changing external environment more comfortably and stand invincible in the fierce competition. Trunsun has been using ISO9001 quality management system to strengthen the quality management of products and services for ten years, and the successful certification of ISO27001:2013 information security management system is an even more solid step for Trunsun to promote the level of information security management and enhance the core competitiveness!

However, as the wave of information technology change comes, network information security will also face more new challenges, so it is a heavy responsibility to protect information security! Trunsun will always adhere to the security management policy of “improving security compliance, preventing all kinds of security risks, ensuring customer data security, and guaranteeing safe business operations”, and will continue to explore and optimize in a dynamic environment, actively fulfill the responsibility of maintaining customer information and data security, and solidify information security maintenance and management into all aspects of business operations, customer service, technology development, and so on. We also solidify the maintenance and management of information security into all aspects of business operation, customer service, and technology research and development.

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NeoTrident iLabPower Sequence Editor Efficiently Catalyzes Bio-New Drug Development

by CompanyNews Center

With the advent of the electronic lab notebook era, based on the standardized cross-team workflow, molecular biologists and chemists are able to promote the research and development of new drugs in a more synergistic and efficient way. However, in the field of biology industrial software, China is still in its infancy and currently relies mainly on foreign imports. Relying on foreign software has some potential drawbacks, mainly in terms of data security and R&D costs.

Data security: Using foreign software usually means that the user’s data will be sent to foreign servers, which may be intercepted during transmission or accessed by unauthorized third parties on the servers. This poses a very serious risk for data that contains sensitive information, such as patient genetic data and new drug development data. In addition, this can also lead to legal issues, as many countries and regions have strict regulations on data export.

R&D Costs: Foreign software usually charges higher fees, especially for some specialized biology research software. This constitutes a considerable burden for research institutions and enterprises, especially those with relatively tight funds. In addition to the direct purchase costs, foreign software may also bring some implied costs. For example, due to differences in the language and cultural background in which the software is used, users may need to invest extra time and effort to learn and familiarize themselves with its use. In addition, obtaining technical support may also become more difficult due to differences in time zones and languages.

Some researchers have tried to use dozens of open source software to transfer data, however, this method is complicated to operate, cannot guarantee data security, and the results are often unsatisfactory, wasting a lot of valuable time.

In order to meet the above challenges, Trunetech proposes a solution: iLabPower Sequence Editor. iLabPower Sequence Editor is an important part of iLabPower R&D management platform, which allows biologists to no longer be constrained by foreign software, and no longer need to put their data in foreign countries. It is equipped with visual sequence editing function, and at the same time, the design process can be recorded in the experimental record book.

 

Figure 1 | iLabPower Sequence Editor: a homegrown biological sequence design tool integrated in the electronic lab notebook.

 

iLabPower Sequence Editor supports the completion of the upstream and downstream processes from sequence creation, sequence editing to sequence validation in one go on the same platform. Taking plasmid construction, a common molecular biology experiment, as an example, the key steps in the classic process, including selecting target genes and vectors, designing primers for PCR amplification of target fragments, selecting appropriate endonuclease for pre-assembly cutting, and checking the product by sequencing results, can all be completed in iLabPower Sequence Editor. The multiple work steps are centralized in one platform, which guarantees the traceability and reproducibility of the data. The recent popularity of CRISPR and cyclic RNA construction have a similar sequence design process as plasmid construction, which is also a potential application scenario for iLabPower Sequence Editor.

 

Figure 2 | iLabPower Sequence Editor The Sequence Editor supports the top-to-bottom sequence design process from sequence creation, to sequence editing, to sequence verification.

Check out the details of iLabPower Sequence Editor 1.2, which will be released soon!

 

Create Sequences

The iLabPower Sequence Editor supports creating sequences in a variety of ways:

  • Importing fasta sequence files
  • Import a fasta sequence file, import a genbank or other annotated sequence file.
  •  Import a fasta sequence file Import a sequence file with annotations such as genbank

iLabPower Sequence Editor supports users to customize the labeling classification of each sequence in the electronic lab notebook, which can be adapted to the actual development scenario of each team for sequence management and searching. The design and modification process of each sequence is fully recorded in the electronic lab notebook, which realizes the fine control of data history in teamwork and guarantees the reproducibility of the experimental results.

After the sequence is imported, iLabPower Sequence Editor can automate the sequence processing, including generating sequence coordinates, switching sequence case, copying/replacing/inserting/deleting specified parts of the sequence, and searching and locating the sequence. In the editor, DNA sequences can be copied in various formats, including forward and reverse strand, or forward and reverse strand of corresponding RNA and protein sequences, which no longer requires users to calculate manually, avoiding manual errors in the basic and tedious process, and saving a lot of time that can be invested in meaningful data interpretation and design.

The common sequence analysis process starts from obtaining gene and vector sequences, usually the result of downloading or sequencing is a single-stranded sequence, which can be imported into iLabPower Sequence Editor to automatically generate complementary strands and construct double-stranded DNA sequences to support the subsequent design work.

The iLabPower Sequence Editor not only supports displaying and editing at the precision of specific base sequences, but also displays the sequence as a whole in the form of linear or circular maps. On the map, annotations, primers, digestion sites and other information can be displayed in a personalized way, which is convenient for the construction and design of plasmids, CRISPR, miRNA and other structures.

 

Figure 3 | iLabPower Sequence Editor creates, manages and visualizes sequences.

Nucleic acid sequence analysis

  •  DNA property calculation and primer design

iLabPower Sequence Editor automatically calculates basic DNA properties, including annealing temperature, GC content, and sequence length, etc., which is very convenient for primer design. iLabPower Sequence Editor also provides an automatic primer design function based on Primer3, which automatically generates pairs of primers or single primers under the sequence range and primer parameters specified by the user and displays primer property parameters for comparison and selection. The primer parameters are displayed for comparison and selection.

 

Figure 4 | Primer design with iLabPower Sequence Editor

  •  Enzymatic site display

In the construction of various vectors, the use of restriction endonucleases is the basic step of sequence shearing. iLabPower Sequence Editor automatically identifies the enzyme cleavage sites in the sequence based on the NEB-Enzyme Finder database and displays them on the sequence and map. You can also search for specific enzyme sites in the editor to speed up the design of sequence cuts and substitutions.

 

Figure 5 | Browsing and searching for cleavage sites with the iLabPower Sequence Editor.

  •  Open Reading Frame Recognition

In the process of gene expression, the existence of open reading frames is one of the main mechanisms that cause the diversity of gene expression, and the diversity of expression products has a significant impact on the quality control in the development of new drugs. iLabPower Sequence Editor can automatically identify the open reading frames, support the identification of multiple start codons, support the user to customize the minimum length of the translation product, and provide an intuitive visual display of the open reading frames. Figure 6 | Using iLabPower Sequence Editor

 

Figure 6 | ORF-based diverse expression analysis using iLabPower Sequence Editor

Amino acid sequence analysis

  •  Protein biochemical characterization

For translatable DNA sequences, iLabPower Sequence Editor can automatically translate them into amino acid sequences corresponding to codons, and support users to select amino acid sequence coordinates and color schemes.

For the generated amino acid sequences, iLabPower Sequence Editor can automatically analyze the amino acid components of proteins, list the percentage of each amino acid, and study the properties of proteins by protein composition analysis. In addition, it is also possible to categorize the amino acids according to their hydrophilic and hydrophobic properties, and find those hydrophobic groups that may be transmembrane regions. In turn, parameters such as isoelectric point, molecular weight, extinction coefficient, instability, etc. of proteins can also be analyzed to study protein properties in general.

 

  • Antibody Design

Antibody drugs are currently a popular research area for new drugs. iLabPower Sequence Editor can automatically identify the CDR region in the sequence, i.e. the highly variable region that plays a key role in antigen recognition, which facilitates antibody design.

 

Figure 7 | iLabPower Sequence Editor shows protein biochemistry and CDR region.

 

Comparative Analysis

  •  BLAST

Blast analysis is a cornerstone of bioinformatics analysis, which has been widely used in basic evolutionary and developmental research, as well as clinical molecular diagnostics and design of new biological drugs. iLabPower Sequence Editor supports one-click jumping, automatically submits the target sequence fragments as query in NCBI-blastn page, and predicts the query sequence by comparing with NCBI database. Possible functions.

  •  Dual Sequence Alignment

iLabPower Sequence Editor supports dual sequence alignment of DNA and amino acid sequences to find the affinity between the two sequences. The comparison algorithm and parameters can be adjusted individually, and the comparison results can be visualized to show the conserved homologous regions and highly variable regions at a glance.

 

Figure 8 | iLabPower Sequence Editor Dual Sequence Comparison Results

New biopharmaceuticals have demonstrated unparalleled effectiveness and potential in the treatment of once-unsolved diseases, such as cancer and genetic diseases. iLabPower Sequence Editor, with its high efficiency, ease-of-use, and safety design concepts, has undoubtedly brought a new path for innovative research in laboratories and biopharmaceutical companies. It realizes that sequence design work can be done in one go, from upstream design to downstream testing, on a platform with highly controllable data security and reproducibility!

In addition, based on the in-depth understanding of the needs and pain points in the field of bio-new drug R&D, NeoTrident is also constantly upgrading the interaction and convenience of the software, enriching the bioinformatics functions provided by the software, and is committed to escorting the intellectual property rights and rapid research and development of China’s bio-innovative drugs!

 

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iLabPower R&D innovative digital platform for large molecule analysis laboratory testing process paperless management solutions

by IndustryNews Center

For large molecule drug analysis laboratories using traditional paper-based management mode, the common management problems and pain points include the following aspects:

Confused management of test request form

Because the test request form is a batch latitude, each analyst will have more than one test request form, taking up a lot of space, and easy to lose, resulting in sample leakage. At the same time, because there are many large molecule drug test items, it is difficult for analysts to quickly distinguish the test items and samples assigned to them in each batch of requisitions.

Difficulty in finding samples and references

For large molecule drugs, the samples and reference preparations are usually frozen and stored in small packages, so a large number of paper ledgers will be generated during storage, which makes it difficult for laboratory personnel to find them. Due to the temperature management requirements of the ultra-low temperature refrigerator, it is necessary to minimize the number of times and time of opening and closing the refrigerator, so every time the sample is accessed, it is necessary to find the freezing box where the sample/reference preparation is located as quickly as possible.

Results Reporting and COA Issuance

After analysts have completed their experiments and record reviews, they still need to find the paper report forms for the corresponding batches and fill in the conclusions of the test results for the corresponding test items, which is time-consuming and laborious, and can easily lead to untimely reporting of results. On the other hand, the sample management team also needs to organize the COA report according to the results and conclusions filled in by the analysts, which also brings a lot of workload.

Archiving and Access to Experimental Records

For the completed paper records, the current offline records are usually managed using coded controlled paper and other ways, the experimenter in the completion of the results report, but also need to register the return of the use of the records issued by the controlled paper code. At the same time, with the increase in the accumulation of test records, the space required by the enterprise archive has also been raised, resulting in a sharp rise in archive management costs. At the same time when there are OOS / OOT / AD and other abnormalities, the historical records of the query and access to the ease of archiving records with the increase in the number of records and consequently a substantial increase.

Aiming at the above management problems and pain points, iLabPower R&D and innovation digital platform developed by Chuangteng Technology provides an overall paperless solution for analytical laboratory management, which includes sample delivery process management, electronic laboratory record book and biological sample management, to help analytical laboratories of large molecule biopharmaceuticals to improve the efficiency of sample management and testing and analysis.

Sample Delivery Process System

iLabPower SIP

iLabPower SIP (Sample Inspection Procedure System) can realize the whole process management from the establishment of quality standards to the distribution of samples and the allocation of test items as well as the issuance of COA reports, and supports the automatic determination of test conclusions as well as the automatic generation of COA reports, which can help the users to better complete the allocation of testing tasks as well as the organization and issuance of COA reports, and ultimately improve the overall operational efficiency of the analytical laboratory. Seamless connection between SIP and ELN. Each testing task can be associated with the corresponding experimental records in ELN, and at the same time, it supports direct access to testing results from ELN to ensure the authenticity, traceability and timeliness of data.

Electronic Laboratory Notebook System

iLabPower ELN

iLabPower ELN and iLabPower SIP to achieve seamless docking, SIP in the distribution of testing tasks synchronized to the ELN, analysts in the ELN to complete the analysis of experiments, and complete the corresponding record review and results reporting work, and the results automatically back to the SIP, effectively enhance the efficiency of the analysis of results reporting. ELN also contains the instrument data analysis, customized ELN also includes basic functions such as instrument data analysis, customized experiment templates, mobile APP photo recording and voice recognition recording, which further improves the efficiency of analysts in organizing experiment records. At the same time, ELN also supports online archiving and full-text search function, which reduces the cost of document storage and improves the convenience of historical record query.

Biological Sample Management System

iLabPower BIMS

iLabPower BIMS is the latest product of iLabPower R&D and innovation platform, which is specially designed for the management of large molecule biological samples, such as proteins, cells, plasmids, strains, etc. It provides users with complete laboratory biological sample management system. It provides users with a complete solution for laboratory biological sample management. It provides visualization interface configuration for commonly used cryopreservation equipment, such as refrigerator, liquid nitrogen tank, basket, freezing rack, freezing box, etc. It also provides sample retrieval and query function, which makes it more convenient to retrieve cryopreserved samples, reference preparations, etc. It also reduces the number of switching times of refrigerator and liquid nitrogen tank as much as possible, so as to avoid unstable nature of samples caused by too high temperature.

Scientist in protection suit holding sample of infected blood with coronavirus in test tube. Doctor working with various bacteria and tissue, pharmaceutical research for antibiotics against covid19.

7 security issues that must be considered for electronic lab notebook selection

by IndustryNews Center

SaaS deployment mode, SaaS software providers will be uniformly deployed in the cloud service provider’s servers, the user through the SaaS software provider to purchase the appropriate software license (License) to use the software and obtain the corresponding services. Users do not need to install and deploy the software before applying the software, nor do they need to carry out regular software upgrades and routine maintenance, but only need to log in to the system to obtain the convenience brought by the system functions.

As the services and data are deployed in the cloud instead of the local server room in the SaaS model, users may have some concerns – can their data be effectively protected? In this paper, we start from the SaaS security issues that users are most concerned about, and explain in detail how to examine the security assurance capabilities of SaaS providers when selecting SaaS ELNs from the aspects of basic security, environmental security, application security, data security, compliance, and the division of security responsibilities.

1, SaaS platform deployment in the private cloud or public cloud

Public cloud platforms have higher availability, security and elasticity than private cloud platforms. It is recommended that public cloud platforms prefer mainstream cloud platforms such as Microsoft Azure, AWS, Aliyun, Tencent Cloud and Huawei Cloud.

2、Security management qualifications of third-party providers

When choosing a SaaS platform, it is necessary to examine the basic security capabilities, security protection capabilities and security qualifications of the third-party SaaS provider.

Take Microsoft Azure as an example, Microsoft Azure Cloud is a cloud platform jointly operated by Microsoft in mainland China and CenturyLink. Microsoft Azure Cloud has completed top global security certifications such as ISO27001, and the platform has also been certified by the Ministry of Public Security’s DJCP (Information System Security Level Protection Classification) and the national standard GB18030 at the same time. The Microsoft Azure cloud security system mainly includes physical and environmental security, basic security, disaster recovery and business continuity, etc. The security of the platform has been widely recognized by professional organizations, and it is one of the most trustworthy cloud platforms in the market today.

All business platforms of Innovation Cloud Community are deployed on Microsoft Azure Cloud IAAS platform, using Microsoft Azure Cloud to provide services such as computing/networking and storage. Innovation Cloud Community chooses Microsoft Azure cloud firewall system to provide peripheral network security, and enjoys the same security level as Microsoft China Office365 and other platforms.

  1. What are the security protection measures for SaaS applications?

The security capability of the SaaS platform is not equivalent to the security capability of the SaaS application, and the SaaS product/service itself needs to have sufficient security capabilities. iLabPower Innovation Cloud Community, for example, SaaS products must have a network level, database system level, environment level, staff level, operating system level and other comprehensive network environment security assurance. The specific measures are as follows:

(1) User Access

   – Access interface security

      ① Adopt more secure https protocol (based on SSL transmission encryption protocol)

      ② URL encrypted by algorithm

   – Privilege security

      ① The login password is encrypted, and each account is bound to the terminal.

      ② UC product authorization restrictions

      ③ Authorization and access based on employee business system roles.

   – Access Control

      Authorization and access based on employee’s business system role Access control ① Employee has a unique account, prohibiting the account login of departed employees.

      ② Account login password error protection mechanism

      ③ Audit: Information system logs and authority audit records are saved by backup for auditing when needed.

   – Data Security

      Data security ① Read-write separation to ensure data integrity and normal operation and reduce downtime.

      ② high availability system of two servers hot standby

      ② Hot standby for two servers in the high availability system ③ Make the database into a distributed database, sharing the bottleneck of each server resource tolerance

      ④ Lightweight distributed file system to solve the problem of mass storage and load balancing.

      ⑤ Adopt IIS10, system upgrade will not affect customer access to the system.

      ⑥ Arrange regular system and database inspection, data backup and anti-path tampering.

      (vii) Effective methods provided by the existing network structure to expand server bandwidth, throughput, processing capacity, and improve flexibility and availability.

(2) System Security

   – Organizational Security

      The Innovation Cloud community team consists of a design security team, an R&D security team, and a maintenance security team.

   – Personnel Security

      Employee behavior meets the requirements of all laws, policies, procedures, and the Innovation Cloud Community Code of Business Conduct; employees have the knowledge, skills, and experience necessary to perform their duties.

   – Delivery Security

      Security throughout the product lifecycle from design, technical deployment, support, and maintenance; service delivery is closely linked to the company’s core processes.

   – System Development and Maintenance

      The R&D and maintenance teams are jointly responsible for the underlying architecture, business logic implementation, and on-line maintenance of the Innovation Cloud Community; collaborating to build a secure cloud service environment for Innovation Cloud Community customers.

   – R&D Process and Standard Security

      A robust R&D process is important for producing high-quality and secure products. The Innovation Cloud Community team incorporates product security baselines into the requirements list and conducts threat analysis of customer usage scenarios to achieve secure product design and development.

   – Disaster Recovery/Business Continuity

      In order to minimize service interruptions caused by hardware failures, natural disasters, or other catastrophes, Innovative Cloud Communities provides a disaster recovery plan for all data, including multiple components to reduce the risk of failure of any individual node: high availability, data protection, and disaster recovery.

4、SaaS platform will conduct regular penetration testing

SaaS platforms are required to conduct regular penetration tests and issue security test reports from relevant security vendors/service providers.

 

  1. Regulatory compliance and related privacy policies

All data in the SaaS platform including access with administrative privileges shall be logged and audited on a regular basis. An assessment of compliance with regulatory standards can help determine compliance and ensure that the right business processes are in place.

The ownership of SaaS platform user data belongs to the user. SaaS service providers are not allowed to use the data without the user’s consent, let alone sell it, and should take legal means to destroy historical data that is unnecessary to keep in a timely manner. saaS service providers have the responsibility to ensure that the user’s data is secure, and to make financial compensation for the user’s losses caused by data leakage and data loss.

The iLabPower Innovation Cloud Community’s Privacy Policy specifies in detail how user information is collected, used, stored, and shared, and the manner in which users are provided with access, updates, control, and protection of such information.

 

  1. How SaaS multi-tenant data is segregated

SaaS is based on multi-tenant architecture, a SaaS will have more than one user’s data saved in the same data storage location.SaaS providers should ensure that any one user can not access the data when accessing the data to the other user’s data, so the provider needs to ensure data isolation in the design of the SaaS application system and data model.

Microsoft Azure provides network isolation for each deployment, and by using input endpoints, it is possible to control which ports can be accessed from the Internet.

(1) Communication between VMs is always routed through trusted packet filters.

  1. Protocols such as Address Resolution Protocol (ARP) and Dynamic Host Configuration Protocol (DHCP), as well as other OSI Layer 2 communications from the VMs, can be controlled using rate limiting and anti-spoofing protection.
  2. The virtual machine is unable to capture any network communication with a destination address other than its own.

(2) The guest’s virtual machine cannot send communications to Azure’s private interfaces or to other guest’s virtual machines, or to Azure Infrastructure Services. A guest’s virtual machine can only communicate with virtual machines owned or controlled by the same guest, and Azure Infrastructure Services endpoints used for public communication.

(3) When a customer places VMs into a virtual private network, those VMs are given their own, completely invisible address space, which is then inaccessible from VMs outside of the deployment or virtual network (unless configured to be visible via a public IP address).

 

7, how to divide responsibility for security compliance

There is a consensus in the industry that in the SaaS model, security compliance responsibilities are shared between the SaaS provider and the customer. For example, if a security incident is caused by a vulnerability in the application system (application security), the responsible party is the cloud platform party; if a security incident is caused by a user using a weak password and identity theft (data security), the responsible party is the tenant party.

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Application of Scientific Data Genome in Man-hour Management of Pharmaceutical R&D Projects

by IndustryNews Center

Man-hour management is a very critical part of the pharmaceutical R&D project management process. Taking CRO (pharmaceutical R&D outsourcing service organization) as an example, its service charge is calculated according to the man-hours spent by project personnel and the unit price of man-hours, and man-hours management directly reflects the project cost; in addition, scientific and accurate man-hours management can also reflect whether the allocation of resources is reasonable or not, and provide a basis for decision-making to optimize the project’s resource allocation, so that the purpose of cost reduction and efficiency increase can be achieved. To achieve the purpose of cost reduction and efficiency.

For CRO enterprises, they undertake many R&D projects, and there are new projects joining in the middle of the process, and the process data formats and standards of different projects are different. Traditional project management software, due to its low degree of freedom, is often unable to help in the face of such a complicated task of working hour statistics, and many enterprises have to export working hour data regularly, and clean and organize a large number of data forms manually, which is a tedious workload, and project management personnel have to face the problem. In the face of such a cumbersome workload, project managers are simply overwhelmed! In addition, manual processing is difficult to ensure that the data is instantly updated, which can easily lead to information lag, and cannot provide agile and powerful support for project decision-making. Moreover, from the perspective of data security, manual processing inevitably leads to data tampering due to various reasons, and these changes are difficult to be traced back, which also makes it difficult for the regulatory authorities to verify the data.

SDH Scientific Data Genome Platform provides a fast, efficient and safe solution to the above labor management problems.

▶ Automatic cleaning and conversion of a large number of data tables, and one-step splicing of new tables.

In the SDH platform, first select “File Connection & Management” in the Data Connection section, and upload the monthly working hours statistics table to SDH.

After entering the data editing page, we can make use of a series of conversion tools such as “Delete Empty Rows” and “Inverse Pivot” to organize and clean the working hours data; meanwhile, the “Conversion Rules” workflow generated together with the conversion and cleaning can be saved. At the same time, the “conversion rules” generated with the conversion and cleaning workflow can be saved, which is convenient for the subsequent one-click cleaning of the work hour data table.

By customizing the saving, we can summarize the work hour statistics table of multiple months into a single data table, and quickly realize the data splicing of multiple months. At the same time, the subsequent addition of the project hours data table can also be realized one-step splicing.

▶ Multi-dimensional statistical report presentation, data synchronization and updating with one click

After completing the data cleaning, we can use the platform’s BI report function for data statistical analysis. The established statistical table can be saved, and when there is a subsequent update of the working hours data, you can directly click on the report to view the latest statistical results, which can efficiently help accurate decision-making.

In addition, project management and materials (reagent) management and other systems within the budget and expenditure, can also be achieved through the SDH platform data fusion project cost statistics and display.

▶ Strict Audit Trail and Permission Management to Ensure Data Security and Traceability

The SDH platform does not allow any modification to the data, while built-in strict audit trail and authority management, all operations are clear at a glance, adding layers of security to the data.